MAPT polyclonal antibody
产品名称： MAPT polyclonal antibody
英文名称： MAPT polyclonal antibody
产品编号： PAB8481
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPT.
- Immunogen:
- A synthetic peptide corresponding to human MAPT.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.1% proclin, 2.0% Block Ace)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (5-10 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Phosphorylation of microtubule-associated protein tau by Ca2+/calmodulin-dependent protein kinase II in its tubulin binding sites.
Yamamoto H, Yamauchi E, Taniguchi H, Ono T, Miyamoto E.Arch Biochem Biophys. 2002 Dec 15;408(2):255-62.
- 2.
- Ca2+- and calmodulin-dependent phosphorylation of microtubule-associated protein 2 and tau factor, and inhibition of microtubule assembly.
Yamamoto H, Fukunaga K, Tanaka E, Miyamoto E.J Neurochem. 1983 Oct;41(4):1119-25.
- Entrez GeneID:
- 4137
- Gene Name:
- MAPT
- Gene Alias:
- DDPAC,FLJ31424,FTDP-17,MAPTL,MGC138549,MSTD,MTBT1,MTBT2,PPND,TAU
- Gene Description:
- microtubule-associated protein tau
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
- Other Designations:
- G protein beta1/gamma2 subunit-interacting factor 1,microtubule-associated protein tau, isoform 4
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Aphasia, Primary Progressive
- Atherosclerosis
- Atherosclerosis
- Atrophy
- Autistic Disorder
- Brain Concussion
- Brain Diseases
- Brain Ischemia
- Cardiovascular Diseases
- Carotid Stenosis
- Cleft Lip
- Cleft Palate
- Cognition
- Cognition Disorders