MEF2A (Human) Recombinant Protein (P01)
产品名称： MEF2A (Human) Recombinant Protein (P01)
英文名称： MEF2A (Human) Recombinant Protein (P01)
产品编号： H00004205-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： 2023-09-19T18:58:01
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human MEF2A full-length ORF ( AAH13437, 1 a.a. - 499 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRRPDLRVVIPPSSKGMMPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
- Theoretical MW (kDa):
- 80.41
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 4205
- GeneBank Accession#:
- BC013437
- Protein Accession#:
- AAH13437
- Gene Name:
- MEF2A
- Gene Alias:
- ADCAD1,RSRFC4,RSRFC9
- Gene Description:
- myocyte enhancer factor 2A
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM
- Other Designations:
- MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
- Related Disease
- Atherosclerosis
- Cardiomyopathy, Hypertrophic
- Cardiovascular Diseases
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Hypertrophy, Left Ventricular
- Insulin Resistance
- Myocardial Infarction
- Myocardial Ischemia
- Polycystic Ovary Syndrome
- Tobacco Use Disorder