PPP1CA monoclonal antibody, clone 4G3
产品名称： PPP1CA monoclonal antibody, clone 4G3
英文名称： PPP1CA monoclonal antibody, clone 4G3
产品编号： MAB1112
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant PPP1CA.
- Immunogen:
- Recombinant protein corresponding to amino acids 30-299 of human PPP1CA.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines.
Hsu LC, Huang X, Seasholtz S, Potter DM, Gollin SM.Oncogene. 2006 Sep 7;25(40):5517-26. Epub 2006 Apr 17.
- 2.
- Protein phosphatase 1--targeted in many directions.
Cohen PT.J Cell Sci. 2002 Jan 15;115(Pt 2):241-56.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of cell lysates of HepG2 (45 ug) were resolved by SDS - PAGE , transferred to NC membrane and probed with PPP1CA monoclonal antibody , clone 4G3 (1 : 1000) (Cat # MAB1112). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 5499
- GeneBank Accession#:
- NM_002708
- Protein Accession#:
- NP_002699
- Gene Name:
- PPP1CA
- Gene Alias:
- MGC15877,MGC1674,PP-1A,PPP1A
- Gene Description:
- protein phosphatase 1, catalytic subunit, alpha isoform
- Omim ID:
- 176875
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- protein phosphatase 1, catalytic subunit, alpha,serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit