ALDH6A1 (C-term) Peptide
产品名称： ALDH6A1 (C-term) Peptide
英文名称： ALDH6A1 (C-term) Peptide
产品编号： P0449
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ALDH6A1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ALDH6A1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Assignment of the PAX6 gene to bovine chromosome 15q25-->q27 by fluorescence in situ hybridization and confirmation by radiation hybrid mapping.
Kuiper H, Williams JL, Distl O, Drogemuller C.Cytogenet Genome Res. 2005;109(4):533.
- 2.
- The human plasma proteome: a nonredundant list developed by combination of four separate sources.
Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, Conrads TP, Veenstra TD, Adkins JN, Pounds JG, Fagan R, Lobley A.Mol Cell Proteomics. 2004 Apr;3(4):311-26. Epub 2004 Jan 12.
- 3.
- Molecular characterization of methylmalonate semialdehyde dehydrogenase deficiency.
Chambliss KL, Gray RG, Rylance G, Pollitt RJ, Gibson KM.J Inherit Metab Dis. 2000 Jul;23(5):497-504.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of ALDH6A1 (arrow) using rabbit ALDH6A1 polyclonal antibody (Cat # PAB3128). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH6A1 gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with ALDH6A1 polyclonal antibody (Cat # PAB3128) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 4329
- Protein Accession#:
- NP_005580;Q02252
- Gene Name:
- ALDH6A1
- Gene Alias:
- MGC40271,MMSADHA,MMSDH
- Gene Description:
- aldehyde dehydrogenase 6 family, member A1
- Omim ID:
- 603178
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq
- Other Designations:
- aldehyde dehydrogenase 6A1,mitochondrial acylating methylmalonate-semialdehyde dehydrogenase
- Related Disease