WNK3 polyclonal antibody
产品名称： WNK3 polyclonal antibody
英文名称： WNK3 polyclonal antibody
产品编号： PAB4586
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of WNK3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human WNK3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:1000)
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.
Verissimo F, Jordan P.Oncogene. 2001 Sep 6;20(39):5562-9.
- 2.
- Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O.DNA Res. 2000 Aug 31;7(4):273-81.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with WNK3 polyclonal antibody (Cat # PAB4586) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 65267
- Protein Accession#:
- Q9BYP7
- Gene Name:
- WNK3
- Gene Alias:
- KIAA1566,PRKWNK3
- Gene Description:
- WNK lysine deficient protein kinase 3
- Omim ID:
- 300358
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM
- Other Designations:
- OTTHUMP00000023369,protein kinase, lysine deficient 3