PBXIP1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PBXIP1抗体

PBXIP1抗体

商家询价

产品名称： PBXIP1抗体

英文名称： PBXIP1Antibody

产品编号： XY12102-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 PBXIP1抗体Applications

In-house applications ELISA, WB, IHC, IF, IP     Application not tested? Please see our Guarantee.
Published applications IF, IHC, WB Publications 6 citations –view here
Species specificity Human; other species not tested.
Published Species Human, mouse
Images
Prev12NextView more validation data
  • 12102-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 12102-1-AP(PBXIP1 antibody) at dilution of 1:1000
  • 12102-1-AP;human lung cancerImmunohistochemical of paraffin-embedded human lung cancer using 12102-1-AP(PBXIP1 antibody) at dilution of 1:100 (under 10x lens)
  • 12102-1-AP;HeLa cellsIP Result of anti-PBXIP1 (IP:12102-1-AP, 3ug; Detection:12102-1-AP 1:800) with HeLa cells lysate 3000ug.
  • 12102-1-AP;HepG2 cellsImmunofluorescent analysis of HepG2 cells using 12102-1-AP( PBXIP1 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HeLa cells, A549 cells, BxPC-3 cells
Positive IP detected in HeLa cells
Positive IHC detected in Human lung cancer tissue
Positive IF detected in HepG2 cells, HeLa cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100
PBXIP1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen InformationPBXIP1抗体
Immunogen PBXIP1 fusion protein ag2746 Full name Pre-B-cell leukemia homeobox interacting protein 1
Calculated molecular
weight		 731aa,81 kDa Observed molecular 
weight		 95 kDa
GenBank accession 
number		 BC016852 Gene ID (NCBI) 57326
Gene symbol PBXIP1 Synonyms HPIP, PBXIP1
Background

PBXIP1 (pre-B-cell leukemia transcription factor-interacting protein 1), also known as HPIP (hematopoietic PBX-interacting protein), is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. PBXIP1 is a nucleo-cytoplasmic shuttling protein, mainly localized in the cytosol and in small amounts in the nucleus (PMID: 10825160). It interacts with PBX1 as well as PBX2 and PBX3. PBXIP1 inhibits the ability of PBX-HOX heterodimers to bind to target sequences and strongly inhibits the transactivation activity of E2A-PBX. PBXIP1 is also reported to be a microtubule-binding protein, which regulates estrogen receptor functions and plays a role in cancer development and progression (PMID: 17043237; 18302941; 23321675).PBXIP1抗体

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