PLA2G4A polyclonal antibody (A01)
产品名称： PLA2G4A polyclonal antibody (A01)
英文名称： PLA2G4A polyclonal antibody (A01)
产品编号： H00005321-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant PLA2G4A.
- Immunogen:
- PLA2G4A (NP_077734, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag.
- Sequence:
- MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Application Image
- ELISA
- Entrez GeneID:
- 5321
- GeneBank Accession#:
- NM_024420
- Protein Accession#:
- NP_077734
- Gene Name:
- PLA2G4A
- Gene Alias:
- MGC126350,PLA2G4,cPLA2-alpha
- Gene Description:
- phospholipase A2, group IVA (cytosolic, calcium-dependent)
- Omim ID:
- 600522
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq
- Other Designations:
- OTTHUMP00000033543,calcium-dependent phospholipid-binding protein,cytosolic phospholipase A2, group IVA,lysophospholipase,phosphatidylcholine 2-acylhydrolase
- Gene Pathway
- alpha-Linolenic acid metabolism
- Arachidonic acid metabolism
- Ether lipid metabolism
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Glycerophospholipid metabolism
- GnRH signaling pathway
- Linoleic acid metabolism
- Long-term depression
- MAPK signaling pathway
- Metabolic pathways
- Vascular smooth muscle contraction
- VEGF signaling pathway
- Related Disease
- Adenomatous Polyposis Coli
- Alzheimer Disease
- Alzheimer disease
- Asthma
- Asthma
- Bipolar Disorder
- Cardiovascular Diseases
- Connective Tissue Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent
- Edema
- Fetal Diseases
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- HIV Infections
- Hyperinsulinism
- Infant, Premature, Diseases
- Infection