PPP1R12B purified MaxPab mouse polyclonal antibody (B01P)
产品名称： PPP1R12B purified MaxPab mouse polyclonal antibody (B01P)
英文名称： PPP1R12B purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00004660-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human PPP1R12B protein.
- Immunogen:
- PPP1R12B (AAH34430, 1 a.a. ~ 386 a.a) full-length human protein.
- Sequence:
- MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEAVLFWPF
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PPP1R12B expression in transfected 293T cell line (H00004660-T01) by PPP1R12B MaxPab polyclonal antibody.
Lane 1: PPP1R12B transfected lysate(42.57 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 4660
- GeneBank Accession#:
- BC034430
- Protein Accession#:
- AAH34430
- Gene Name:
- PPP1R12B
- Gene Alias:
- MGC131980,MGC87886,MYPT2
- Gene Description:
- protein phosphatase 1, regulatory (inhibitor) subunit 12B
- Omim ID:
- 603768
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Myosin light chain phosphatase (MLCP) consists of three subunits- catalytic subunit, large subunit/myosin binding subunit (MBS) and small subunit (sm-M20). This gene is a multi-functional gene which encodes both MBS and sm-M20. MLCP regulates myosins and the dephosphorylation is enhanced by the presence of MBS. The sm-M20 is suggested to play a regulatory role in muscle contraction by binding to MBS. MBS is also encoded by another gene, myosin light chain phosphatase target subunit 1. sm-M20 shows higher binding affinity to this gene product than to myosin light chain phosphatase target subunit 2-MBS even though the two MBS proteins are highly similar. Although both MBSs increase the activity of MLCP, myosin light chain phosphatase target subunit 1-MBS is a more efficient activator. There are four alternatively spliced transcript variants described; two alter the MBS coding region and two alter the sm-M20 coding region of this gene. [provided by RefSeq
- Other Designations:
- myosin phosphatase regulatory subunit,myosin phosphatase, target subunit 2
- Gene Pathway