KIR2DL3 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： KIR2DL3 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： KIR2DL3 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00003804-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human KIR2DL3 protein.
- Immunogen:
- KIR2DL3 (NP_056952.2, 1 a.a. ~ 341 a.a) full-length human protein.
- Sequence:
- MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of KIR2DL3 expression in transfected 293T cell line (H00003804-T02) by KIR2DL3 MaxPab polyclonal antibody.
Lane 1: KIR2DL3 transfected lysate(37.90 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3804
- GeneBank Accession#:
- NM_015868.2
- Protein Accession#:
- NP_056952.2
- Gene Name:
- KIR2DL3
- Gene Alias:
- CD158B2,CD158b,GL183,KIR-023GB,KIR-K7b,KIR-K7c,KIRCL23,MGC129943,NKAT,NKAT2,NKAT2A,NKAT2B,p58
- Gene Description:
- killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
- Omim ID:
- 604938
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq
- Other Designations:
- NK-receptor,killer cell immunoglobulin-like receptor 2DL3,natural killer associated transcript 2,natural killer cell inhibitory receptor KIR2DL3,p58 natural killer cell receptor,p58.2 MHC class-I specific NK receptor
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Acute Disease
- Angina Pectoris
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Behcet Syndrome
- Carcinoma, Hepatocellular
- Celiac Disease
- Cervical Intraepithelial Neoplasia
- Colitis, Ulcerative
- Crohn Disease
- Cytomegalovirus Infections
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Familial Mediterranean Fever
- Familial Mediterranean fever