ITK (Center) Peptide
产品名称: ITK (Center) Peptide
英文名称: ITK (Center) Peptide
产品编号: P2754
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ITK.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human ITK.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A.
Brazin KN, Mallis RJ, Fulton DB, Andreotti AH.Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1899-904. Epub 2002 Feb 5.
- 2.
- Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity.
Hawkins J, Marcy A.Protein Expr Purif. 2001 Jul;22(2):211-9.
- 3.
- Mapping of the gene for the tyrosine kinase Itk to a region of conserved synteny between mouse chromosome 11 and human chromosome 5q.
Janis EM, Siliciano JD, Isaac DD, Griffin CA, Hawkins AL, Kozak CA, Desiderio S.Genomics. 1994 Sep 1;23(1):269-71.
- Entrez GeneID:
- 3702
- Protein Accession#:
- ITK_HUMAN
- Gene Name:
- ITK
- Gene Alias:
- EMT,LYK,MGC126257,MGC126258,PSCTK2
- Gene Description:
- IL2-inducible T-cell kinase
- Omim ID:
- 186973
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq
- Other Designations:
- homolog of mouse T-cell itk/tsk,tyrosine-protein kinase ITK/TSK,tyrosine-protein kinase LYK