Anti-PCNA Polyclonal Antibody-蛋白质/抗原/多肽-试剂-生物在线

Anti-PCNA Polyclonal Antibody

商家询价

产品名称： Anti-PCNA Polyclonal Antibody

英文名称： Anti-PCNA Polyclonal Antibody

产品编号： K101310P

产品价格： 0

产品产地：北京

品牌商标： Solarbio

更新时间： 2024-06-28T09:15:13

使用范围： null

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
邮编 : 101102
所在区域 : 北京
电话 : 178****1073
传真 :
邮箱 : 3193328036@qq.com

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产品详情

Anti-PCNA Polyclonal Antibody
品牌：solarbio | 货号：K101310P

商品货号： 商品品牌： 规格 基本售价： 选择规格
K101310P-50ul solarbio 50ul 960.00元 
K101310P-100ul solarbio 100ul 1600.00元

商品货号：	商品品牌：	规格	基本售价：	选择规格
K101310P-50ul	solarbio	50ul	960.00元
K101310P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-PCNA Polyclonal Antibody
别名 ATLD2;cb16;Cyclin;HGCN872;MGC8367
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 29kDa
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human PCNA
性状 液体
Public Immunogen Range A synthetic peptide of human PCNA
Subcellular Locations Nucleus
Swiss Prot P12004
克隆类型 Polyclonal Antibody
背景资料 Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerases processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3-5 exonuclease and 3-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while Lys-63-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.

英文名称	Anti-PCNA Polyclonal Antibody
别名	ATLD2;cb16;Cyclin;HGCN872;MGC8367
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Human Mouse Rat
蛋白分子量	29kDa
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human PCNA
性状	液体
Public Immunogen Range	A synthetic peptide of human PCNA
Subcellular Locations	Nucleus
Swiss Prot	P12004
克隆类型	Polyclonal Antibody
背景资料	Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerases processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3-5 exonuclease and 3-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while Lys-63-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.