血管紧张素II受体样蛋白1抗体-抗体-抗体-生物在线
血管紧张素II受体样蛋白1抗体

血管紧张素II受体样蛋白1抗体

商家询价

产品名称: 血管紧张素II受体样蛋白1抗体

英文名称: Apelin Receptor

产品编号: 2430

产品价格: null

产品产地: 上海

品牌商标: 雅吉

更新时间: null

使用范围: WB ELISA Flow-Cyt ICC IF

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中文名称 血管紧张素II受体样蛋白1抗体
别    名 APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.  

 

研究领域 心血管  细胞生物  免疫学  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Rabbit, )
产品应用 WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Apelin receptor:41-140/380 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq

Function:
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P35414

Gene ID:
187

Database links:

Entrez Gene: 429337 Chicken

Entrez Gene: 615435 Cow

Entrez Gene: 187 Human

Entrez Gene: 23796 Mouse

Entrez Gene: 83518 Rat

Omim: 600052 Human

SwissProt: P35414 Human

SwissProt: Q9WV08 Mouse

SwissProt: Q9JHG3 Rat

Unigene: 438311 Human

Unigene: 29368 Mouse

Unigene: 7965 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 
产品图片 Sample:
Lane 1: Heart (Mouse) Lysate at 40 ug
Lane 2: Heart (Rat) Lysate at 40 ug
Lane 3: Cerebrum (Mouse) Lysate at 40 ug
Lane 4: Cerebrum (Rat) Lysate at 40 ug
Lane 5: Spinal cord (Mouse) Lysate at 40 ug
Lane 6: Spinal cord (Rat) Lysate at 40 ug
Primary: Anti-Apelin Receptor (bs-2430R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44/58 kD
Observed band size: 50 kD
Sample:
Stomach (Mouse) Lysate at 40 ug
Primary: Anti-Apelin Receptor (bs-2430R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD
Positive control(blue): mouse Splenocytes
Isotype Antibody (orenge): Rabbit IgG, Dilution: 1ug in 100 u1 X PBS containing 0.5% BSA
Secondary Antibody(light blue): Goat anti-rabbit IgG-FITC,Dilution: 1:200 in 1 X PBS containing 0.5% BSA
Primary Antibody catalog number (green): bs-2430R, Dilution: 1ug in 100ul 1X PBS containing 0.5% BSA