CLEC2D 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CLEC2D 抗体

CLEC2D 抗体

商家询价

产品名称： CLEC2D 抗体

英文名称： CLEC2D Antibody

产品编号： XY13188-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 CLEC2D 抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 13188-1-AP;Jurkat cellsJurkat cells were subjected to SDS PAGE followed by western blot with 13188-1-AP(CLEC2D antibody) at dilution of 1:500
Positive WB detected in Jurkat cells
Recommended dilution WB : 1:200-1:2000
 CLEC2D 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CLEC2D fusion protein ag3862 Full name C-type lectin domain family 2, member D
Calculated molecular
weight		 154aa,18 kDa Observed molecular 
weight		 33 kDa
GenBank accession 
number		 BC019883 Gene ID (NCBI) 29121
Gene symbol CLEC2D Synonyms CLAX, CLEC2D, Lectin like NK cell receptor, Lectin like transcript 1, LLT 1, LLT1, OCIL, Osteoclast inhibitory lectin
Background CLEC2D 抗体

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741). Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700). CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and that their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512). It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786). CLEC2D 抗体

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