BIRC5 (phospho S20) polyclonal antibody (DyLight 649)
产品名称： BIRC5 (phospho S20) polyclonal antibody (DyLight 649)
英文名称： BIRC5 (phospho S20) polyclonal antibody (DyLight 649)
产品编号： PAB15179
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of BIRC5.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S20 of human BIRC5.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This antibody is useful for Western blot, where a band is seen ~16.5 KDa.
- Form:
- Liquid
- Conjugation:
- DyLight 649
- Storage Buffer:
- In 50 mM sodium borate
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- Western Blot (3 ug/mL)
The optimal working dilution should be determined by the end user.
- Application Image
- Western Blot
- Entrez GeneID:
- 332
- Protein Accession#:
- O15392
- Gene Name:
- BIRC5
- Gene Alias:
- API4,EPR-1
- Gene Description:
- baculoviral IAP repeat-containing 5
- Omim ID:
- 603352
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
- Other Designations:
- apoptosis inhibitor 4,baculoviral IAP repeat-containing protein 5,survivin variant 3 alpha
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Carcinoma, Adenosquamous
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cell Transformation, Neoplastic
- Colorectal Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid, Acute
- Lung Neoplasms
- Lymphatic Metastasis
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Neovascularization, Pathologic
- Pancreatic Neoplasms