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上海信裕生物科技有限公司
FHIT抗体

FHIT抗体

商家询价

产品名称： FHIT抗体

英文名称： FHITAntibody

产品编号： XY 13362-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 FHIT抗体

Applications
In-house applications ELISA     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
 
Recommended dilution  
 FHIT抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen FHIT fusion protein ag4181 Full name Fragile histidine triad gene
Calculated molecular
weight		 147aa,17 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC032336 Gene ID (NCBI) 2272
Gene symbol FHIT Synonyms AP3A hydrolase, AP3Aase, Bis(5 adenosyl) triphosphatase, Dinucleosidetriphosphatase, FHIT, FRA3B, fragile histidine triad gene
Background FHIT抗体

The candidate tumor suppressor gene, FHIT(Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity(PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription. FHIT抗体

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