PLAT (Human) ELISA Kit
产品名称: PLAT (Human) ELISA Kit
英文名称: PLAT (Human) ELISA Kit
产品编号: KA0157
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- PLAT (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human t-PA.
- Calibration Range:
- 15.6 to 1000 pg/mL
- Limit of Detection:
- 6.4 pg/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
- Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Cell Culture Supernatant, Serum
- Sample Volume:
- 10 uL
- Label:
- HRP-conjugate
- Detection Method:
- Colorimetric
- Intra-Assay:
- 3.60%
- Inter-Assay:
- 6.50%
- Spiking Recovery:
- 98.00%
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- Recombinant tissue plasminogen activator induces blood-brain barrier breakdown by a matrix metalloproteinase-9-independent pathway after transient focal cerebral ischemia in mouse.
Copin JC, Bengualid DJ, Da Silva RF, Kargiotis O, Schaller K, Gasche Y.Eur J Neurosci. 2011 Oct;34(7):1085-1092. doi: 10.1111/j.1460-9568.2011.07843.x. Epub 2011 Sep 6.
- Application Image
- Quantification
- Entrez GeneID:
- 5327
- Gene Name:
- PLAT
- Gene Alias:
- DKFZp686I03148,T-PA,TPA
- Gene Description:
- plasminogen activator, tissue
- Omim ID:
- 173370
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- alteplase,plasminogen activator, tissue type,reteplase,t-plasminogen activator,tissue plasminogen activator (t-PA)
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Aneurysm, Ruptured
- Arterial Occlusive Diseases
- Arteriosclerosis
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Brain Infarction
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Cerebral Palsy
- Cerebrovascular Accident
- Chorioamnionitis
- Connective Tissue Diseases
- Coronary Artery Disease
- Coronary Disease