BMP7 monoclonal antibody, clone 4E7
产品名称: BMP7 monoclonal antibody, clone 4E7
英文名称: BMP7 monoclonal antibody, clone 4E7
产品编号: MAB1073
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant BMP7.
- Immunogen:
- Recombinant protein corresponding to amino acids 293-431 of human BMP7.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix.
Gregory KE, Ono RN, Charbonneau NL, Kuo CL, Keene DR, Bachinger HP, Sakai LY.J Biol Chem. 2005 Jul 29;280(30):27970-80. Epub 2005 Jun 1.
- 2.
- Structural basis of BMP signalling inhibition by the cystine knot protein Noggin.
Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Belmonte JC, Choe S.Nature. 2002 Dec 12;420(6916):636-42.
- 3.
- Regulation of BMP7 expression during kidney development.
Godin RE, Takaesu NT, Robertson EJ, Dudley AT.Development. 1998 Sep;125(17):3473-82.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of mouse kidney (MK) and rat heart (RH) extracts were resolved by SDS - PAGE , transferred to PVDF membrane and probed with BMP7 monoclonal antibody , clone 4E7 (1 : 1000) (Cat # MAB1073) . Protein was visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 655
- GeneBank Accession#:
- NM_001719
- Protein Accession#:
- NP_001710
- Gene Name:
- BMP7
- Gene Alias:
- OP-1
- Gene Description:
- bone morphogenetic protein 7
- Omim ID:
- 112267
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq
- Other Designations:
- OTTHUMP00000031357,osteogenic protein 1
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