IL1RAPL1 monoclonal antibody (M04), clone 1C10
产品名称： IL1RAPL1 monoclonal antibody (M04), clone 1C10
英文名称： IL1RAPL1 monoclonal antibody (M04), clone 1C10
产品编号： H00011141-M04
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant IL1RAPL1.
- Immunogen:
- IL1RAPL1 (NP_055086.1, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- FEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMES
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Mutations in the calcium-related gene IL1RAPL1 are associated with autism.
Piton A, Michaud JL, Peng H, Aradhya S, Gauthier J, Mottron L, Champagne N, Lafreniere RG, Hamdan FF; S2D team, Joober R, Fombonne E, Marineau C, Cossette P, Dube MP, Haghighi P, Drapeau P, Barker PA, Carbonetto S, Rouleau GA.Hum Mol Genet. 2008 Dec 15;17(24):3965-74. Epub 2008 Sep 18.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged IL1RAPL1 is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 11141
- GeneBank Accession#:
- NM_014271
- Protein Accession#:
- NP_055086.1
- Gene Name:
- IL1RAPL1
- Gene Alias:
- IL1R8,IL1RAPL,MRX10,MRX21,MRX34,OPHN4,TIGIRR-2
- Gene Description:
- interleukin 1 receptor accessory protein-like 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq
- Other Designations:
- OTTHUMP00000023097,X-linked interleukin-1 receptor accessory protein-like 1,interleukin 1 receptor-8,mental retardation, X-linked 10,oligophrenin-4,three immunoglobulin domain-containing IL-1 receptor-related 2
- Related Disease
- Autistic Disorder
- Avoidance Learning
- Cardiovascular Diseases
- Chorioamnionitis
- Cognition
- Diabetes Mellitus, Type 2
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Intelligence Tests
- Memory
- Mental Retardation
- Obstetric Labor, Premature
- Pre-Eclampsia
- Premature Birth
- Psychotic Disorders
- Schizophrenia