FITC标记的丝氨酸/苏氨酸蛋白激酶SIK2抗体
产品名称： FITC标记的丝氨酸/苏氨酸蛋白激酶SIK2抗体
英文名称： Anti-SNF1LK2/FITC
产品编号： HZ-6930R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-SNF1LK2/FITC Conjugated antibody
FITC标记的丝氨酸/苏氨酸蛋白激酶SIK2抗体
| 英文名称 | Anti-SNF1LK2/FITC |
| 中文名称 | FITC标记的丝氨酸/苏氨酸蛋白激酶SIK2抗体 |
| 别 名 | QIK; Qin induced kinase; Qin-induced kinase; Salt inducible kinase 2; Salt inducible protein kinase 2; Salt inducible serine/threonine kinase 2; Salt-inducible protein kinase 2; Serine/threonine protein kinase SIK2; Serine/threonine protein kinase SNF1 like kinase 2; Serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; SIK 2; SIK-2; SIK2; SIK2_HUMAN; SNF1 like kinase; SNF1 like kinase 2; SNF1LK2; DKFZp434K1115; EC 2.7.11.1; KIAA0781; LOH11CR1I. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 104kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNF1LK2/SIK2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. Subunit: Interacts with and phosphorylates TORC2/CRTC2. Subcellular Location: Cytoplasm Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. Contains 1 protein kinase domain. Contains 1 UBA domain. Database links: UniProtKB/Swiss-Prot: Q9H0K1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
在胰岛素刺激的脂肪细胞中磷酸化ELS1的SE-794'，可能调节胰岛素信号转导的效率。通过磷酸化和抑制TORCs，CREB特异性共激活物抑制CREB活性。