EXD3,EXD3蛋白抗体

产品编号HZ-14655R
英文名称EXD3
中文名称EXD3蛋白抗体
别 名EXDL3; EXD3; Exonuclease 3''-5'' domain-containing protein 3; Exonuclease 3'-5' domain containing 3; FLJ20433; HBE269; LOC54932; mut-7; MUT7_HUMAN; Probable exonuclease mut-7 homolog; probable exonuclease mut-7 homolog, isoform 5.
说 明 书0.1ml 0.2ml
研究领域细胞生物 发育生物学 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
EXD3,EXD3蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量97kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EXD3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EXD3,EXD3蛋白抗体PubMedPubMed
产品介绍background:
EXD3 is an 876 amino acid protein that contains one 3’-5’ exonuclease domain, suggesting a possible role in nucleotide cleavage. The gene encoding EXDL3 maps to chromosome 9 and is expressed as four isoforms that are produced via alternative splicing events. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias.

Tissue Specificity:

Similarity:
Belongs to the mut-7 family.
Contains 1 3'-5' exonuclease domain.

Gene ID:
54932

EXD3,EXD3蛋白抗体Database links:
Entrez Gene: 54932 Human
SwissProt: Q8N9H8 Human
Unigene: 495553 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.