MTHFD1L抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MTHFD1L抗体

MTHFD1L抗体

商家询价

产品名称： MTHFD1L抗体

英文名称： MTHFD1LAntibody

产品编号： XY16113-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 MTHFD1L抗体

Applications
Tested Applications: ELISA, WB, IHC, IP
Cited applications WB
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Cited species Mouse
Positive WB detected in HepG2 cells, COLO 320 cells, HeLa cells, mouse ovary tissue
Positive IP detected in HeLa cells
Positive IHC detected in Human colon cancer tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
 MTHFD1L抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 16113-1-AP;HepG2 cellHepG2 cells were subjected to SDS PAGE followed by western blot with 16113-1-AP(MTHFD1L antibody) at dilution of 1:500
  • 16113-1-AP;Colon cancerImmunohistochemical of paraffin-embedded human colon cancer using 16113-1-AP(MTHFD1L antibody) at dilution of 1:100 (under 10x lens)
  • 16113-1-AP;Colon cancerImmunohistochemical of paraffin-embedded human colon cancer using 16113-1-AP(MTHFD1L antibody) at dilution of 1:100 (under 40x lens)
  • 16113-1-AP;HeLa cellsIP Result of anti-MTHFD1L (IP:16113-1-AP, 4ug; Detection:16113-1-AP 1:1000) with HeLa cells lysate 2000ug.
Product Information MTHFD1L抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: MTHFD1L fusion protein ag9036 Full Name: Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Caculated Molecular
Weight:		 978aa,106 kDa Observed Molecular 
Weight:		 106kd
GenbankNo BC017477 GeneID: 25902
Symbol MTHFD1L Synonyms DJ292B18.2, DKFZp586G1517, FLJ21145, FTHFSDC1, MTC1THFS, MTHFD1L
Background

MTHFD1L(Monofunctional C1-tetrahydrofolate synthase, mitochondrial) is also named as FTHFSDC1(Formyltetrahydrofolate synthetase). MTHFD1L enzyme is present in mitochondria from normal embryonic tissues and embryonic fibroblast cell lines, and embryonic mitochondria possess the ability to synthesize formate from glycine. It catalyzes the final step in the mitochondrial conversion of 1-C units to formate in embryos. Moreover, MTHFD1L levels were substantially higher in embryonic mitochondria than in adult liver mitochondria and embryonic mitochondria exhibited greater formate production(PMID:19948730). It has 2 isoforms produced by alternative splicing. MTHFD1L抗体

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