APBB2,铁蛋白Fe65样蛋白1抗体

产品编号HZ-11627R
英文名称APBB2
中文名称铁蛋白Fe65样蛋白1抗体
别 名Amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65 like); Amyloid beta A4 precursor protein binding family B member 2; Amyloid beta A4 precursor protein-binding family B member 2; APBB 2; APBB2; APBB2_HUMAN; Fe65 like 1; Fe65 like; Fe65 like protein; FE65L 1; FE65L; FE65L1; Protein Fe65-like 1; Rirl 1; Rirl1; TR2 L; TR2L; Zfra; Zinc finger like protein.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 Alzheimer's
抗体来源Rabbit
APBB2,铁蛋白Fe65样蛋白1抗体克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量83kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human APBB2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
APBB2,铁蛋白Fe65样蛋白1抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Function:
May modulate the internalization of beta-amyloid precursor protein.

Subunit:
Binds to the intracellular domain of the beta-amyloid precursor protein.

Similarity:
Contains 2 PID domains.
Contains 1 WW domain.

Database links:
Entrez Gene: 323 Human
Entrez Gene: 11787 Mouse
Omim: 602710 Human
SwissProt: Q92870 Human
SwissProt: Q9DBR4 Mouse
Unigene: 479602 Human
Unigene: 482700 Mouse
Unigene: 5159 Mouse

APBB2,铁蛋白Fe65样蛋白1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.