HDAC6 monoclonal antibody (M01), clone 1E2
产品名称： HDAC6 monoclonal antibody (M01), clone 1E2
英文名称： HDAC6 monoclonal antibody (M01), clone 1E2
产品编号： H00010013-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant HDAC6.
- Immunogen:
- HDAC6 (NP_006035, 1128 a.a. ~ 1215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- DVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.
Bantscheff M, Hopf C, Savitski MM, Dittmann A, Grandi P, Michon AM, Schlegl J, Abraham Y, Becher I, Bergamini G, Boesche M, Delling M, Dumpelfeld B, Eberhard D, Huthmacher C, Mathieson T, Poeckel D, Reader V, Strunk K, Sweetman G, Kruse U, Neubauer G, Ramsden NG, Drewes G.Nat Biotechnol. 2011 Jan 23. [Epub ahead of print]
- Applications
- Western Blot (Cell lysate)
- HDAC6 monoclonal antibody (M01), clone 1E2 Western Blot analysis of HDAC6 expression in HeLa NE ( Cat # L013V3 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of HDAC6 expression in transfected 293T cell line by HDAC6 monoclonal antibody (M01), clone 1E2.
Lane 1: HDAC6 transfected lysate (Predicted MW: 131.4 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 10013
- GeneBank Accession#:
- NM_006044
- Protein Accession#:
- NP_006035
- Gene Name:
- HDAC6
- Gene Alias:
- FLJ16239,HD6,JM21
- Gene Description:
- histone deacetylase 6
- Omim ID:
- 300272
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq
- Other Designations:
- OTTHUMP00000032398