CD82 (C-term) Peptide
产品名称： CD82 (C-term) Peptide
英文名称： CD82 (C-term) Peptide
产品编号： P1855
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CD82.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CD82.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Requirement of the p130CAS-Crk coupling for metastasis suppressor KAI1/CD82-mediated inhibition of cell migration.
Zhang XA, He B, Zhou B, Liu L.J Biol Chem. 2003 Jul 18;278(29):27319-28. Epub 2003 May 8.
- 2.
- EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells.
Zhang XA, Lane WS, Charrin S, Rubinstein E, Liu L.Cancer Res. 2003 May 15;63(10):2665-74.
- 3.
- [Role of tumor metastasis suppressor gene KAI1 in development of colorectal cancer]
Yang J, Liu FX, Yan XC, He GY, Liu LM.Ai Zheng. 2003 May;22(5):533-6.
- Applications
- Western Blot (Tissue lysate)
- The CD82 polyclonal antibody (Cat # PAB4830) is used in Western blot to detect CD82 in mouse liver tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with CD82 polyclonal antibody (Cat # PAB4830) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 3732
- Protein Accession#:
- NP_002222
- Gene Name:
- CD82
- Gene Alias:
- 4F9,C33,GR15,IA4,KAI1,R2,SAR2,ST6,TSPAN27
- Gene Description:
- CD82 molecule
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- C33 antigen,CD82 antigen,R2 leukocyte antigen,inducible membrane protein R2,kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)),suppression of tumorigenicity 6,suppress
- Interactome
- Gene Pathway