AAK1 polyclonal antibody
产品名称： AAK1 polyclonal antibody
英文名称： AAK1 polyclonal antibody
产品编号： PAB17258
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of AAK1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at internal region of human AAK1.
- Sequence:
- C-GSPRTSQQNVYNPSE
- Host:
- Goat
- Theoretical MW (kDa):
- 104
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A novel AAK1 splice variant functions at multiple steps of the endocytic pathway.
Henderson DM, Conner SD.Mol Biol Cell. 2007 Jul;18(7):2698-706. Epub 2007 May 9.
- Entrez GeneID:
- 22848
- Protein Accession#:
- NP_055726.3
- Gene Name:
- AAK1
- Gene Alias:
- DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,MGC138170,MGC164568,MGC164570
- Gene Description:
- AP2 associated kinase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- adaptor-associated kinase 1
- Related Disease