CNOT2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CNOT2抗体

CNOT2抗体

商家询价

产品名称： CNOT2抗体

英文名称： CNOT2Antibody

产品编号： XY10313-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CNOT2抗体

Applications
In-house applications ELISA, WB, IF     Application not tested? Please see our Guarantee.
Published applications WB Publications 2 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 10313-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 10313-1-AP( CNOT2 Antibody) at dilution of 1:300
  • 10313-1-AP;HEK-293 cellsImmunofluorescent analysis of ( 10% Formaldehyde ) fixed HEK-293 cells using 10313-1-AP( CNOT2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HEK-293 cells
Positive IF detected in HEK-293 cells
Recommended dilution WB : 1:200-1:1000
IF : 1:50-1:500
 CNOT2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information CNOT2抗体
Immunogen CNOT2 fusion protein ag0347 Full name CCR4-NOT transcription complex, subunit 2
Calculated molecular
weight		 60 kDa Observed molecular 
weight		 60 kDa
GenBank accession 
number		 BC002597 Gene ID (NCBI) 4848
Gene symbol CNOT2 Synonyms CCR4 associated factor 2, CDC36, CNOT2, FLJ26456, HSPC131, MSTP046, NOT2, NOT2H
Background CNOT2抗体

The Ccr4–Not complex is evolutionarily conserved and controls gene expression both at the level of transcription initiation and of mRNA degradation. And this complex can regulate pol II transcription. Promoter targeting of CCR4-NOT transcription complex subunit 2 (CNOT2) results in strong repression of pol II transcription. CNOT2-mediated repression is sensitive to the HDAC (histone deacetylase) inhibitor, TSA (trichostatin A). CNOT2抗体

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