MATK (Human) Recombinant Protein (Q02)
产品名称： MATK (Human) Recombinant Protein (Q02)
英文名称： MATK (Human) Recombinant Protein (Q02)
产品编号： H00004145-Q02
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human MATK partial ORF ( NP_647612, 422 a.a. - 507 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- RAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPASVSGQDADGSTSPRSQEP
- Theoretical MW (kDa):
- 35.2
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 4145
- GeneBank Accession#:
- NM_139355
- Protein Accession#:
- NP_647612
- Gene Name:
- MATK
- Gene Alias:
- CHK,CTK,DKFZp434N1212,HHYLTK,HYL,HYLTK,Lsk,MGC1708,MGC2101
- Gene Description:
- megakaryocyte-associated tyrosine kinase
- Omim ID:
- 600038
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- Csk-homologous kinase,Csk-type protein tyrosine kinase,HYL tyrosine kinase,hematopoietic consensus tyrosine-lacking kinase,hydroxyaryl-protein kinase,leukocyte carboxyl-terminal src kinase related,protein kinase HYL,tyrosine kinase MATK,tyrosine-protein k