产品概述：Purified recombinant protein of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), full length, with C-terminal DDK tag, expressed in sf9, 20ug

蛋白长度：A DNA sequence from GoldORF clone, [GH31605V], encoding human full-length TTI1

表达系统：Sf9

种属：Human

标签类型：C-DDK

分子量：121.9 kDa

通用名：TTI1

总结：Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

别名：KIAA0406; smg-10